1. In October 2025, Mounjaro became India’s top-selling drug by value, overtaking which antibiotic?
[A] Amoxicillin
[B] Augmentin
[C] Doxycyclin
[D] Azithromycin
Show Answer
Correct Answer: B [Augmentin]
Notes:
Eli Lilly’s weight-loss drug Mounjaro became India’s top-selling drug by value in October 2025. It overtook GlaxoSmithKline’s (GSK) Augmentin, a widely used antibiotic. Mounjaro earned ₹1 billion ($11.38 million) in October, while Augmentin made ₹800 million. By volume, Augmentin sold 5,784 units, whereas Mounjaro sold only 85 units due to its high price. Mounjaro helps control blood sugar and slow digestion and belongs to the GLP-1 receptor agonist class used for obesity and diabetes. It was launched in India in March 2025 and has earned ₹3.33 billion till October. Mounjaro’s consumption was 10 times higher than rival Wegovy by Novo Nordisk, launched in June 2025. Eli Lilly sold 262,000 units, while Novo Nordisk sold 26,000 units in October.
2. Which university secured a national patent for a machine learning-based technology to extract rainfall data from radar signals?
[A] Delhi University
[B] Banaras Hindu University
[C] Cochin University of Science and Technology
[D] Lucknow University
Show Answer
Correct Answer: C [Cochin University of Science and Technology]
Notes:
The Cochin University of Science and Technology (CUSAT) has received a national patent for a machine learning-based radar technology to extract accurate rainfall data. The system was developed at the Advanced Centre for Atmospheric Radar Research (ACARR). It uses a Hybrid Adaptive Bi-Gaussian Fitting Algorithm with a Gaussian Mixture Model (GMM) to separate rain and air turbulence echoes. The innovation helps radars clean their data in real time, improving rainfall and wind accuracy up to 5 km in the troposphere. It enhances flood forecasting and early warning systems for Kerala, a state prone to extreme monsoon events.
3. ESCAPADE (Escape and Plasma Acceleration and Dynamics Explorers) mission is an initiative of which space agency?
[A] China National Space Administration (CNSA)
[B] European Space Agency (ESA)
[C] Indian Space Research Organisation (ISRO)
[D] National Aeronautics and Space Administration (NASA)
Show Answer
Correct Answer: D [National Aeronautics and Space Administration (NASA)]
Notes:
Blue Origin recently launched NASA’s ESCAPADE mission to Mars. ESCAPADE (Escape and Plasma Acceleration and Dynamics Explorers) is NASA’s first coordinated multi-spacecraft orbital science mission to Mars. It consists of twin orbiters named Blue and Gold that will observe Mars from different locations simultaneously. The mission is part of NASA’s SIMPLEx (Small Innovative Missions for Planetary Exploration) program.
4. Which species is the natural host of the Marburg virus disease that was recently reported in Ethiopia?
[A] Aedes aegypti mosquito
[B] Fruit Bat
[C] Honeybee
[D] Rat
Show Answer
Correct Answer: B [Fruit Bat]
Notes:
Recently, the World Health Organization (WHO) confirmed Ethiopia’s first-ever outbreak of Marburg Virus Disease (MVD). MVD is a severe and often fatal hemorrhagic fever caused by the Marburg virus. It was first identified in 1967 in Marburg, Germany. The causative agents are Marburg virus (MARV) and Ravn virus (RAVV) of the species Orthomarburgvirus marburgense. The natural host is the fruit bat Rousettus aegyptiacus of the Pteropodidae family. It spreads from infected bats to humans and then through contact with bodily fluids or contaminated surfaces.
5. What kind of disease is African Swine Fever (ASF) that was recently seen in news?
[A] Fungal disease
[B] Viral disease
[C] Bacterial disease
[D] None of the Above
Show Answer
Correct Answer: B [Viral disease]
Notes:
The Assam Government recently banned inter-district movement of live pigs to stop the spread of African Swine Fever (ASF), a rising concern in the region. African Swine Fever (ASF) is a highly contagious and deadly viral disease affecting pigs and wild boar, with mortality up to 90–100%. It is not zoonotic, meaning it does not infect humans or other livestock. First found in sub-Saharan Africa, ASF is now present across Europe, Asia and Africa, with India reporting its first cases in 2020 in Assam and Arunachal Pradesh.
6. What is the name of India’s first indigenous CRISPR-based gene therapy for Sickle Cell Disease?
[A] SCD-CURE
[B] GEN-EDIT 1
[C] BIRSA 101
[D] HematoGene
Show Answer
Correct Answer: C [BIRSA 101]
Notes:
India’s first indigenous CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-based gene therapy for Sickle Cell Disease (SCD), named BIRSA 101, was recently launched by the Union Minister of State (Independent Charge) for Science & Technology. It is developed by CSIR (Council of Scientific and Industrial Research) – Institute of Genomics and Integrative Biology (IGIB). BIRSA 101 uses CRISPR-Cas9 gene-editing technology to precisely correct the genetic mutation causing SCD. The therapy is administered as a one-time infusion, after which the body produces normal red blood cells instead of sickle-shaped ones.
7. What is the name of India’s first manned deep-sea submersible mission?
[A] Gaganyaan
[B] Samudrayaan
[C] Sagaryaan
[D] Chandrayaan
Show Answer
Correct Answer: B [Samudrayaan]
Notes:
Samudrayaan is India’s first manned deep-ocean submersible mission to reach 6,000 metres depth. Testing is delayed due to late supply of syntactic foam from France, now expected by year-end after testing in Norway. The project is led by National Institute of Ocean Technology under the Ministry of Earth Sciences. A steel model has been tested up to 100 metres; a 500-metre trial is planned by April next year. The final titanium hull, built by Indian Space Research Organisation, will be tested in Russia. The mission will carry three crew members to collect seabed soil and rocks for future deep-sea mining.
8. Which telescope was used to discover the spiral galaxy “Alaknanda” ?
[A] Hubble Space Telescope
[B] Spitzer Space Telescope
[C] Chandra X-ray Observatory
[D] James Webb Space Telescope
Show Answer
Correct Answer: D [James Webb Space Telescope]
Notes:
Researchers at National Centre for Radio Astrophysics – Tata Institute of Fundamental Research (NCRA–TIFR), Pune, discovered a new spiral galaxy named Alaknanda. It lies 12 billion light years away and shows a perfect spiral structure. The name comes from the Alaknanda River and the Hindi word for the Milky Way. The galaxy spans 30,000 light years, with two clear spiral arms around a bright central bulge. It forms stars rapidly, producing 60 solar masses per year. It resembles a young Milky Way, formed when our galaxy was only 10% of its current age. The discovery was made using National Aeronautics and Space Administration (NASA)’s James Webb Space Telescope (JWST).
9. What is “Artemisinin” that was recently mentioned in news?
[A] Invasive weed
[B] Antimalarial drug
[C] Newly discovered species of Spider
[D] A pesticide used in crop protection
Show Answer
Correct Answer: B [Antimalarial drug]
Notes:
A new study warns that heavy use of artemisinin and favourable conditions can create new hotspots of drug resistance, with resistance markers slowly rising in parts of Africa. Artemisinin is an antimalarial drug obtained from the sweet wormwood plant called Artemisia annua. It was discovered in the 1970s and became a major breakthrough when malaria parasites developed resistance to older drugs like chloroquine. It is effective against all malaria-causing parasites of the Plasmodium genus, mainly during the blood stage. Artemisinin quickly reduces parasites but stays in the body for a short time, so it is combined with other drugs. The World Health Organization recommends artemisinin-based combination therapies as the standard treatment for Plasmodium falciparum malaria.
10. Michaela Benthaus, who recently became the first wheelchair user to travel to space, belongs to which country?
[A] Russia
[B] Australia
[C] Germany
[D] France
Show Answer
Correct Answer: C [Germany]
Notes:
Michaela Benthaus, a German engineer, became the first wheelchair user to travel to space. German engineer Michaela Benthaus became the first person with paraplegia to travel to space. The suborbital mission was conducted by Blue Origin, Jeff Bezos’ space tourism company. This was the company’s 16th crewed flight, using the New Shepard NS-37 rocket.