1. Scientists at which institute recently discovered how white blood cells adapt their internal skeletons to combat pathogens?
[A] CSIR–Institute of Genomics and Integrative Biology (IGIB)
[B] CSIR–National Chemical Laboratory (NCL)
[C] CSIR–Indian Institute of Chemical Biology (IICB)
[D] CSIR–Centre for Cellular and Molecular Biology (CCMB)
Show Answer
Correct Answer: D [CSIR–Centre for Cellular and Molecular Biology (CCMB)]
Notes:
Scientists at CSIR-Centre for Cellular and Molecular Biology (CCMB) discovered how white blood cells adapt their skeletons to fight pathogens. The study was published in Nature Structural & Molecular Biology. Cell shape depends on a dense, branched actin network near the membrane. Actin molecules push the membrane and create new meshworks for movement. A protein called SPIN90 regulates actin monomers and pairs with the Arp2/3 complex. Together, they grow new actin filaments in two directions about 150° apart. These filaments act as scaffolds to form branched actin mesh, reshaping the cell and aiding motility. This discovery explains rapid immune response and has implications for cancer, immune disorders, and wound healing.
2. Which country has recently developed a bone glue named “Bone-02”, capable of repairing fractures in just three minutes?
[A] Japan
[B] China
[C] Australia
[D] India
Show Answer
Correct Answer: B [China]
Notes:
Chinese researchers have developed a bone glue named Bone-02, unveiled on 10 September 2025 in Zhejiang Province. It can repair fractures and shattered bone fragments in just 3 minutes, even in blood-rich environments. The glue is bio-absorbable, removing the need for a second surgery to remove implants. It may replace metal implants like plates and screws used in conventional surgeries.
3. Which institute in Delhi has launched the city’s first central tissue bank for bone grafting in dental surgeries?
[A] All India Institute of Medical Sciences (AIIMS)
[B] Maulana Azad Medical College
[C] Lady Hardinge Medical College
[D] Vardhman Mahavir Medical College
Show Answer
Correct Answer: B [Maulana Azad Medical College]
Notes:
Maulana Azad Medical College (MAMC), Delhi, launched the city’s first Central Tissue Bank for bone grafting in dental surgeries. The facility was inaugurated by Delhi Health Minister Dr Pankaj Kumar Singh. Bone grafting helps reverse jawbone loss and supports dental implants, dentures, and tissue regeneration. The tissue bank provides ready access to high-quality bone and soft tissue grafts, reducing cost and addressing limited availability.
4. The Gaia Telescope is a space observatory of which space agency?
[A] Indian Space Research Organisation (ISRO)
[B] China National Space Administration (CNSA)
[C] European Space Agency (ESA)
[D] Japan Aerospace Exploration Agency (JAXA)
Show Answer
Correct Answer: C [European Space Agency (ESA)]
Notes:
A new 3D map of stellar nurseries has been created using data from the Global Astrometric Interferometer for Astrophysics (GAIA) telescope. The map covers star-forming regions within 4,000 light-years of the Sun in all directions. It shows glowing hydrogen gas clouds, helping scientists study star formation and interstellar gas dynamics. The study combines Gaia dust maps with radiation effects from 87 massive O-type stars emitting ultraviolet light that ionises hydrogen gas. The simulation aligns with older hydrogen emission maps but provides higher precision. GAIA, launched in 2013 by the European Space Agency (ESA), aims to create the most precise 3D map of the Milky Way Galaxy. The telescope is positioned at Lagrange Point 2 (L2), 1.5 million km from Earth, for a stable cosmic view.
5. Which space organization has launched the Interstellar Mapping and Acceleration Probe (IMAP) mission?
[A] Japan Aerospace Exploration Agency (JAXA)
[B] National Aeronautics and Space Administration (NASA)
[C] European Space Agency (ESA)
[D] Indian Space Research Organisation (ISRO)
Show Answer
Correct Answer: B [National Aeronautics and Space Administration (NASA)]
Notes:
National Aeronautics and Space Administration (NASA) has recently launched the Interstellar Mapping and Acceleration Probe (IMAP) mission. Its main goal is to study how solar particles are energised and how the heliosphere shields Earth. Heliosphere is a giant bubble formed by the Sun’s solar wind that covers the entire solar system. Interstellar Mapping and Acceleration Probe (IMAP) will map the heliosphere’s boundary, trace energetic particles, and improve space weather forecasting. It is positioned at the first Earth-Sun Lagrange Point (L1), about 1 million miles from Earth towards the Sun. It will provide near real-time data on solar wind and energetic particles to monitor space weather hazards.
6. Lecanemab drug, that was recently seen in news, is used to treat which disease?
[A] Multiple Sclerosis
[B] Tuberculosis
[C] Alzheimer’s Disease
[D] Huntington’s Disease
Show Answer
Correct Answer: C [Alzheimer’s Disease]
Notes:
Australia recently approved Lecanemab for early-stage Alzheimer’s disease. Dementia causes progressive memory and thinking problems and is now Australia’s leading cause of death. Alzheimer’s disease accounts for 60-80% of dementia cases. Lecanemab is a monoclonal antibody drug that targets amyloid proteins in the brain. It aims to slow disease progression by tackling the cause of Alzheimer’s, not just symptoms. The drug works by using antibodies to mark amyloid for removal by brain immune cells, preventing toxicity to brain cells.
7. Rotovac vaccine, that was recently seen in news, is used for the prevention/treatment of which disease?
[A] Measles
[B] Tuberculosis
[C] Rotavirus
[D] Polio
Show Answer
Correct Answer: C [Rotavirus]
Notes:
A recent study found that the indigenous rotavirus vaccine ‘Rotavac’ is as effective in real-world use as in clinical trials. Rotavac is an oral, live attenuated, monovalent liquid vaccine against rotavirus. It was developed through a public-private partnership involving the Department of Biotechnology (DBT), Bharat Biotech, and the U.S. National Institutes of Health (NIH). Rotavirus is a viral disease that commonly causes diarrhoeal illness in children. There is no specific medicine to treat rotavirus infection, and vaccination provides the best protection. This study highlights Rotavac’s continued role in child health.
8. Which country recently developed its first indigenously discovered antibiotic, Nafithromycin?
[A] Myanmar
[B] Nepal
[C] India
[D] Sri Lanka
Show Answer
Correct Answer: C [India]
Notes:
India has recently developed its first indigenously discovered antibiotic, Nafithromycin. It was developed with support from the Biotechnology Industry Research Assistance Council (BIRAC). The antibiotic is marketed under the trade name “Miqnaf.” It is the first molecule fully conceptualized, developed, and clinically validated in India. Nafithromycin addresses Antimicrobial Resistance (AMR) and is effective against resistant respiratory infections. It is especially useful for cancer patients and poorly controlled diabetics. The drug treats Community-Acquired Bacterial Pneumonia (CABP) and targets both typical and atypical pathogens. No similar antibiotic in this class has been developed globally for over 30 years.
9. Which rocket was used by ISRO to successfully launch India’s heaviest communication satellite CMS-03?
[A] PSLV-C58
[B] GSLV Mk II
[C] LVM3-M5
[D] SSLV-D2
Show Answer
Correct Answer: C [LVM3-M5]
Notes:
The Indian Space Research Organisation (ISRO) successfully launched the LVM3-M5 rocket from Satish Dhawan Space Centre, Sriharikota at 5:35 pm. The rocket carried CMS-03, India’s heaviest communication satellite weighing 4,400 kilograms. It was the fifth operational flight of the Launch Vehicle Mark-3 (LVM3) launcher. CMS-03 was launched into a Geosynchronous Transfer Orbit (GTO). The satellite will provide multi-band communication services across India and nearby ocean regions. It will enhance secure data, voice, and video connectivity for civilian and strategic applications. The mission highlights India’s capability in heavy satellite launches and strengthens its communication network.
10. Batten disease, that was recently seen in news, primarily affects which part of the human body?
[A] Heart
[B] Lungs
[C] Kidneys
[D] Brain
Show Answer
Correct Answer: D [Brain]
Notes:
Recently, researchers found that male and female brains respond differently as Batten Disease progresses, opening new paths for treatment. Batten Disease is a rare genetic disorder affecting the brain and nervous system. It is congenital, progressive, and terminal, leading to steady decline in nervous system function. Symptoms include loss of vision and seizures, beginning in infancy, childhood, or rarely adulthood. Life expectancy varies from early childhood to the twenties depending on the form.