1. What kind of disease is Crohn’s disease that was recently seen in news?
[A] A respiratory disorder
[B] Autoimmune neurological disorder
[C] A heart disease
[D] A chronic inflammatory bowel disease
Show Answer
Correct Answer: D [A chronic inflammatory bowel disease ]
Notes:
Recent research shows that eating diets high in Ultra Processed Foods (UPFs) can worsen gut inflammation and increase Crohn’s disease flare-ups. Crohn’s Disease is a chronic Inflammatory Bowel Disease (IBD) that causes swelling and irritation in the digestive tract. It usually affects the small intestine and the beginning of the large intestine. Inflammation can spread deep into the bowel layers, causing pain and serious complications. Common symptoms include diarrhea, abdominal cramps, and weight loss. It mostly develops between ages 20 and 29. The exact cause is unknown but may involve genes, immune reactions, and the microbiome. There is no cure, but treatment helps control symptoms and maintain remission.
2. Which Indian research institute has developed a nanotechnology-based method using the coffee-ring effect to detect toxic molecules like Rhodamine B?
[A] Indian Institute of Science (IISc), Bengaluru
[B] Raman Research Institute (RRI), Bengaluru
[C] National Chemical Laboratory (NCL), Pune
[D] Bhabha Atomic Research Centre (BARC), Mumbai
Show Answer
Correct Answer: B [Raman Research Institute (RRI), Bengaluru]
Notes:
Scientists at the Raman Research Institute (RRI), India developed a sensitive method to detect toxic molecules like Rhodamine B. The method uses the coffee-ring effect combined with nanotechnology for enhanced detection. The coffee-ring effect occurs when a droplet evaporates, and capillary flow moves particles from the center to the edge, forming a ring-shaped deposition pattern. Rhodamine B is a water-soluble synthetic dye with bright pink fluorescence. It is widely used in fluorescence microscopy, flow cytometry, and ELISA biochemical assays. Rhodamine B is toxic and carcinogenic, affecting skin, eyes, and the respiratory system. This method provides a rapid and effective tool for detecting hazardous dyes in research and environmental monitoring.
3. Rotovac vaccine, that was recently seen in news, is used for the prevention/treatment of which disease?
[A] Measles
[B] Tuberculosis
[C] Rotavirus
[D] Polio
Show Answer
Correct Answer: C [Rotavirus]
Notes:
A recent study found that the indigenous rotavirus vaccine ‘Rotavac’ is as effective in real-world use as in clinical trials. Rotavac is an oral, live attenuated, monovalent liquid vaccine against rotavirus. It was developed through a public-private partnership involving the Department of Biotechnology (DBT), Bharat Biotech, and the U.S. National Institutes of Health (NIH). Rotavirus is a viral disease that commonly causes diarrhoeal illness in children. There is no specific medicine to treat rotavirus infection, and vaccination provides the best protection. This study highlights Rotavac’s continued role in child health.
4. Which country recently developed its first indigenously discovered antibiotic, Nafithromycin?
[A] Myanmar
[B] Nepal
[C] India
[D] Sri Lanka
Show Answer
Correct Answer: C [India]
Notes:
India has recently developed its first indigenously discovered antibiotic, Nafithromycin. It was developed with support from the Biotechnology Industry Research Assistance Council (BIRAC). The antibiotic is marketed under the trade name “Miqnaf.” It is the first molecule fully conceptualized, developed, and clinically validated in India. Nafithromycin addresses Antimicrobial Resistance (AMR) and is effective against resistant respiratory infections. It is especially useful for cancer patients and poorly controlled diabetics. The drug treats Community-Acquired Bacterial Pneumonia (CABP) and targets both typical and atypical pathogens. No similar antibiotic in this class has been developed globally for over 30 years.
5. Which Indian lunar mission made the first-ever observation of the effect of the Sun’s coronal mass ejection (CME) on the Moon?
[A] Chandrayaan-1
[B] Chandrayaan-2
[C] Chandrayaan-3
[D] Aditya-L1
Show Answer
Correct Answer: B [Chandrayaan-2]
Notes:
Chandrayaan-2, India’s second lunar mission, made the first direct observation of the Sun’s Coronal Mass Ejection (CME) effects on the Moon. The observation was made by CHACE-2 (Chandra’s Atmospheric Composition Explorer-2), a payload onboard the orbiter. Indian Space Research Organisation (ISRO) reported that the dayside lunar exosphere pressure increased when the CME impacted the Moon. The total number density of neutral atoms or molecules increased more than tenfold, confirming theoretical predictions for the first time. Chandrayaan-2, launched on 22 July 2019 via GSLV Mk-III M1, carried eight experiment payloads; however, the Vikram lander lost communication during its soft-landing attempt.
6. Fibromyalgia, that was recently seen in news, is a chronic health condition that primarily affects which part of the human body?
[A] Bones
[B] Muscles and soft tissues
[C] Heart and lungs
[D] Kidneys and liver
Show Answer
Correct Answer: B [Muscles and soft tissues]
Notes:
Fibromyalgia is a real, chronic health condition affecting 2–3% of the global population. It causes long-term pain and tenderness in muscles and soft tissues. Common symptoms include fatigue, sleep disturbances, memory issues, stress, anxiety, and depression. The exact cause is unknown, but affected individuals have heightened sensitivity to pain. Symptoms often appear in flare-ups that come and go. Other symptoms include headaches, migraines, digestive issues, restless leg syndrome, and temporomandibular jaw disorders. There is no cure, but treatment helps control symptoms.
7. Which institute has developed CRYODIL for buffalo semen cryopreservation?
[A] National Dairy Research Institute (NDRI), Karnal
[B] National Institute of Animal Nutrition and Physiology (NIANP), Bengaluru
[C] Central Institute for Research on Buffaloes, Hisar
[D] Indian Veterinary Research Institute (IVRI), Bareilly
Show Answer
Correct Answer: B [National Institute of Animal Nutrition and Physiology (NIANP), Bengaluru]
Notes:
Scientists at the National Institute of Animal Nutrition and Physiology (NIANP), Bengaluru, under the Indian Council of Agricultural Research (ICAR), have developed CRYODIL. CRYODIL is a ready-to-use, egg yolk-free semen extender for buffaloes. It is the first such solution developed in India for buffalo semen cryopreservation. It has a long shelf life of 18 months or more. The post-thaw progressive motility of sperm in CRYODIL is significantly higher than in traditional egg-yolk-based extenders. It improves sperm movement and viability after freezing and thawing, increasing fertilisation success.
8. What type of instrument is a scintillometer that was recently installed at the Tamil Nadu Rice Research Institute (TRRI)?
[A] A soil testing device
[B] An optical instrument
[C] A radiation detector
[D] A humidity sensor
Show Answer
Correct Answer: B [An optical instrument]
Notes:
Recently, a scintillometer was installed at the Tamil Nadu Rice Research Institute (TRRI) in Aduthurai, Tamil Nadu. It is an optical instrument used to measure heat and moisture exchange between the land surface and the atmosphere. The device transmits a light beam between two fixed points to collect data. Turbulent air causes minute fluctuations in the beam, called scintillations, which are analysed to estimate heat transfer. It was installed as part of the TRRI Critical Zone Observatory (CZO) to enhance climate and crop research.
9. The Visible Emission Line Coronagraph (VELC) is the primary payload of which Indian space mission?
[A] Chandrayaan-3
[B] Chandrayaan-2
[C] Mangalyaan-2
[D] Aditya-L1
Show Answer
Correct Answer: D [Aditya-L1]
Notes:
In November 2025, scientists from the Indian Institute of Astrophysics (IIA) collaborated with the National Aeronautics and Space Administration (NASA) to estimate key parameters of a Coronal Mass Ejection (CME). They used data from the Visible Emission Line Coronagraph (VELC) payload onboard India’s Aditya-L1 mission. VELC is the main payload of Aditya-L1, India’s first solar observatory placed 1.5 million kilometres from Earth. It is an internally occulted solar coronagraph capable of imaging, spectroscopy, and spectro-polarimetry near the solar limb.
10. Which cities have been selected for the development of the four Hydrogen Valley Innovation Clusters (HVICs) in India?
[A] Pune, Jodhpur, Bhubaneswar, Kerala
[B] Mumbai, Jaipur, Hyderabad, Tamil Nadu
[C] Bengaluru, Lucknow, Indore, Kerala
[D] Bhopal, Jaipur, Varanasi, Karnataka
Show Answer
Correct Answer: A [Pune, Jodhpur, Bhubaneswar, Kerala]
Notes:
The Union Minister of State (Independent Charge) for Science and Technology announced the development of four Hydrogen Valley Innovation Clusters (HVICs) across India. Hydrogen Valley Innovation Clusters (HVICs) aim to demonstrate the full green hydrogen value chain, from production, storage, transport to utilization. The project has a total investment of ₹485 crore. HVICs aim to build a local hydrogen ecosystem, connecting supply and demand across transport, industry, and energy, while fostering research, innovation, and skills. The four clusters are being developed in Pune, Jodhpur, Bhubaneswar, and Kerala.