1. Which institutions recently created the world’s first entirely AI-generated genome?
[A] California Institute of Technology and Harvard University
[B] Massachusetts Institute of Technology (MIT) and University of Oxford
[C] Harvard University and University of Cambridge
[D] Stanford University and the Arc Institute
Show Answer
Correct Answer: D [Stanford University and the Arc Institute]
Notes:
Researchers at Stanford University and the Arc Institute created the world’s first entirely AI-generated genome. The AI-designed virus can infect and kill bacteria, acting as a bacteriophage. Artificial Intelligence (AI) model named Evo was used, employing genome “language models” to design complete viral genomes. Evo was trained on about 2 million viral genomes to learn DNA patterns, gene order, and composition. Scientists guided Evo to mimic phiX174, a small bacteriophage with 11 genes and approximately 5,000 DNA letters. This achievement marks a significant advancement beyond AI-designed proteins or small multi-gene systems. It demonstrates AI’s potential to innovate in synthetic biology and genome engineering.
2. Which institute conducted the first successful wheat cultivation experiment in the Thar desert using ‘soilification’ technology?
[A] Banaras Hindu University
[B] Punjab Agricultural University
[C] Central Soil Salinity Research Institute
[D] Central University of Rajasthan
Show Answer
Correct Answer: D [Central University of Rajasthan]
Notes:
Recently, Central University of Rajasthan (CUoR) conducted the first successful wheat cultivation in arid land using desert ‘soilification’ technology. The experiment aims to stop the expansion of western Rajasthan’s Thar desert towards the National Capital Region. Desert sand was converted into soil using polymers and indigenous bioformulation, enhancing water retention and soil structure. The project was supported by Krishi Vigyan Kendra (KVK) and the State Horticulture Department. The experiment proves that even barren desert land can become productive with biotechnology.
3. What is the name of India’s first space astronomy observatory which recently completed 10 years of operation?
[A] AstroSat
[B] Chandrayaan
[C] INSAT-3C
[D] Vikram
Show Answer
Correct Answer: A [AstroSat]
Notes:
India’s first dedicated space astronomy observatory, AstroSat, completed 10 years of operation on 28 September 2025. It was launched on 28 September 2015 by PSLV-C30 (Polar Satellite Launch Vehicle-C30) XL from Satish Dhawan Space Centre, Sriharikota. Though designed for 5 years, it continues to provide valuable data after a decade. AstroSat studies the universe across multi-wavelengths: UV (Ultraviolet), Visible, Low and High Energy X-rays. It was developed by ISRO (Indian Space Research Organisation) with collaboration from Indian institutes and partners from Canada and the UK.
4. The Gaia Telescope is a space observatory of which space agency?
[A] Indian Space Research Organisation (ISRO)
[B] China National Space Administration (CNSA)
[C] European Space Agency (ESA)
[D] Japan Aerospace Exploration Agency (JAXA)
Show Answer
Correct Answer: C [European Space Agency (ESA)]
Notes:
A new 3D map of stellar nurseries has been created using data from the Global Astrometric Interferometer for Astrophysics (GAIA) telescope. The map covers star-forming regions within 4,000 light-years of the Sun in all directions. It shows glowing hydrogen gas clouds, helping scientists study star formation and interstellar gas dynamics. The study combines Gaia dust maps with radiation effects from 87 massive O-type stars emitting ultraviolet light that ionises hydrogen gas. The simulation aligns with older hydrogen emission maps but provides higher precision. GAIA, launched in 2013 by the European Space Agency (ESA), aims to create the most precise 3D map of the Milky Way Galaxy. The telescope is positioned at Lagrange Point 2 (L2), 1.5 million km from Earth, for a stable cosmic view.
5. Recently, where is the Titanium and Superalloy Materials Plant inaugurated in Uttar Pradesh?
[A] Lucknow
[B] Kanpur
[C] Gorakhpur
[D] Meerut
Show Answer
Correct Answer: A [Lucknow]
Notes:
Defence Minister Rajnath Singh inaugurated the Titanium and Superalloy Materials Plant at PTC Industries, Lucknow, marking a big step towards self-reliance in defence materials. The plant is part of the Strategic Materials Technology Complex under Aatmanirbhar Bharat vision. The plant will help make components for fighter jets, missiles, naval systems, and satellites. The plant will help make components for fighter jets, missiles, naval systems, and satellites. It supports the Uttar Pradesh Defence Industrial Corridor, generating jobs for youth, MSMEs, and start-ups.
6. Which African country reported an outbreak of the Lassa fever in 2025?
[A] Botswana
[B] Ghana
[C] Mali
[D] Nigeria
Show Answer
Correct Answer: D [Nigeria]
Notes:
In Nigeria, the Lassa fever outbreak has claimed 172 lives since January 2025. The Nigeria Centre for Disease Control and Prevention (NCDC) reported 924 confirmed cases out of 8,041 suspected cases till October 2025. The case fatality rate stands at 18.6%, higher than 17% in 2024. The most affected age group is 21 to 30 years. The outbreak is worsened by poor sanitation, low awareness, and delayed treatment. Lassa fever is a viral haemorrhagic illness caused by the Lassa virus from the Arenavirus family. Infection spreads through food or household items contaminated by urine or faeces of infected Mastomys rats. The World Health Organization (WHO) stresses early diagnosis and quick treatment for survival.
7. Which institute has developed CRYODIL for buffalo semen cryopreservation?
[A] National Dairy Research Institute (NDRI), Karnal
[B] National Institute of Animal Nutrition and Physiology (NIANP), Bengaluru
[C] Central Institute for Research on Buffaloes, Hisar
[D] Indian Veterinary Research Institute (IVRI), Bareilly
Show Answer
Correct Answer: B [National Institute of Animal Nutrition and Physiology (NIANP), Bengaluru]
Notes:
Scientists at the National Institute of Animal Nutrition and Physiology (NIANP), Bengaluru, under the Indian Council of Agricultural Research (ICAR), have developed CRYODIL. CRYODIL is a ready-to-use, egg yolk-free semen extender for buffaloes. It is the first such solution developed in India for buffalo semen cryopreservation. It has a long shelf life of 18 months or more. The post-thaw progressive motility of sperm in CRYODIL is significantly higher than in traditional egg-yolk-based extenders. It improves sperm movement and viability after freezing and thawing, increasing fertilisation success.
8. The Samriddh Gram Phygital Services Pilot Project was recently launched by which organization?
[A] Telecom Regulatory Authority of India (TRAI)
[B] Bharat Sanchar Nigam Limited (BSNL)
[C] Telecom Centres of Excellence (TCoE)
[D] Ministry of Power
Show Answer
Correct Answer: C [Telecom Centres of Excellence (TCoE)]
Notes:
The Telecom Centres of Excellence (TCoE) recently signed agreements with key partners to launch the Samriddh Gram Phygital Services Pilot Project. The project aims to transform rural India by combining physical and digital (phygital) services. It integrates on-ground service delivery with strong digital infrastructure to empower rural citizens. The initiative uses BharatNet connectivity to ensure smooth and sustainable access to essential services. Three villages have been selected for the pilot — Ari and Umri in Madhya Pradesh, Narakoduru in Andhra Pradesh, and Chaurawala in Uttar Pradesh. Each village will have a Samriddhi Kendra serving as an integrated digital service hub.
9. What is the name of India’s first indigenous CAR-T Cell Therapy recently unveiled at the Emerging Science, Technology & Innovation Conclave 2025?
[A] CARIND-1
[B] NexCAR19
[C] BioCure-India
[D] None of the Above
Show Answer
Correct Answer: B [NexCAR19]
Notes:
In a historic milestone, Prime Minister Narendra Modi unveiled NexCAR19, India’s first indigenous CAR-T Cell Therapy, at the Emerging Science, Technology & Innovation Conclave (ESTIC) 2025 in Delhi. It is developed by ImmunoACT, an IIT Bombay spin-off. It is supported by the Department of Biotechnology (DBT) and Biotechnology Industry Research Assistance Council (BIRAC). NexCAR19 is the world’s first humanised CAR-T therapy, truly “Made in India, for the world.” CAR-T Cell Therapy is an immunotherapy that reprograms a patient’s immune cells to fight blood cancers like Acute Lymphocytic Leukemia (ALL).
10. In November 2025, Energy Efficiency Services Limited (EESL) announced India’s largest Geothermal Energy Technology (GET) pilot project in which state?
[A] Odisha
[B] Andhra Pradesh
[C] Gujarat
[D] Karnataka
Show Answer
Correct Answer: B [Andhra Pradesh]
Notes:
In November 2025, Energy Efficiency Services Limited (EESL), a Joint Venture (JV) under the Ministry of Power (MoP), announced India’s largest Geothermal Energy Technology (GET) pilot project in Andhra Pradesh (AP). The project will be implemented at two tourism hubs — Araku Valley and Visakhapatnam (Vizag). It uses geothermal systems like Earth Air Tunnel (EAT) Systems and Ground Source Heat Pumps (GSHP). The system works by using the earth’s constant underground temperature at a depth of 7–8 meters (m) for eco-friendly heating and cooling. The technology has a short payback period of 3–4 years, ideal for hotels and tourism infrastructure.