1. The Crew Health and Performance Exploration Analog (CHAPEA) is a series of missions conducted by which space organization?
[A] Indian Space Research Organisation (ISRO)
[B] National Aeronautics and Space Administration (NASA)
[C] China National Space Administration (CNSA)
[D] European Space Agency (ESA)
Show Answer
Correct Answer: B [National Aeronautics and Space Administration (NASA)]
Notes:
National Aeronautics and Space Administration (NASA) has unveiled the second Crew Health and Performance Exploration Analog (CHAPEA) habitat. It is designed for analogue missions simulating year-long stays on Mars. The second mission will begin in late 2025 with four crew members. The 1,700 square foot, 3D-printed habitat will be used to test living in isolation. CHAPEA (Crew Health and Performance Exploration Analog) is a program of analog missions that simulate year-long stays on the Martian surface. The inaugural CHAPEA mission began in June 2023 and concluded in July 2024, providing valuable insights into the challenges of living and working on Mars.
2. Which institute developed a gold nanocluster-based biosensor for early detection of Parkinson’s Disease?
[A] Indian Institute of Science (IISc), Bengaluru
[B] Institute of Nano Science and Technology (INST), Mohali
[C] All India Institute of Medical Sciences (AIIMS), Delhi
[D] Indian Council of Medical Research (ICMR)
Show Answer
Correct Answer: B [Institute of Nano Science and Technology (INST), Mohali]
Notes:
Researchers at the Institute of Nano Science and Technology (INST), Mohali, are developing a nanotechnology-based tool for early detection of Parkinson’s Disease (PD). Parkinson’s Disease (PD) is a rapidly growing neurological disorder in India, often diagnosed after significant neurodegeneration. The team focused on α-synuclein, a protein that changes from harmless to toxic forms, damaging brain cells. They created gold nanoclusters (AuNCs), ultrasmall particles coated with amino acids to selectively bind normal or toxic protein forms. The tool enables early-stage detection, improving treatment, quality of life, and reducing healthcare costs.
3. Which company has launched the Learning Accelerator program in India to empower the education ecosystem with Artificial Intelligence (AI)?
[A] OpenAI
[B] Microsoft AI
[C] Scale AI
[D] Nvidia
Show Answer
Correct Answer: A [OpenAI]
Notes:
OpenAI has launched the Learning Accelerator program in India to empower the education ecosystem with Artificial Intelligence (AI). India is one of the largest ChatGPT markets, with millions of students using AI for assignments, research, and learning. The initiative will distribute 5 lakh ChatGPT licences to students and educators across schools, universities, and research institutes. Government schools (Classes 1–12) will receive ChatGPT access through the Ministry of Education for lesson planning and personalized student engagement. Technical institutes under All India Council for Technical Education (AICTE) will get AI tools for skill-building.
4. The Solar Orbiter mission is a joint mission conducted by which two space organizations?
[A] European Space Agency (ESA) and National Aeronautics and Space Administration (NASA)
[B] Indian Space Research Organisation (ISRO) and Japan Aerospace Exploration Agency (JAXA)
[C] China National Space Administration (CNSA) and European Space Agency (ESA)
[D] Japan Aerospace Exploration Agency (JAXA) and National Aeronautics and Space Administration (NASA)
Show Answer
Correct Answer: A [European Space Agency (ESA) and National Aeronautics and Space Administration (NASA)]
Notes:
European Space Agency (ESA) Solar Orbiter, a joint project with NASA, was launched in 2020 to study the Sun closely. It became the first spacecraft to image the Sun’s poles. A new study in Astronomy and Astrophysics traced the origin of Solar Energetic Electrons (SEE) emitted by the Sun. Solar Energetic Electrons (SEE) linked to solar flares arise from small surface explosions, while others are released gradually with Coronal Mass Ejections (CME), huge eruptions of plasma and magnetic fields. The Solar Orbiter flew through electron streams and studied the space environment between the Sun and spacecraft. Understanding SEE and CMEs is crucial for space weather prediction, protecting satellites, GPS, power grids, and astronauts. The mission aims to study the Sun’s 11-year magnetic cycle, corona heating, solar wind formation, and acceleration.
5. Which institute discovered that protein p47 acts as a “mechanical chaperone”, enhancing protein stability under mechanical stress?
[A] Indian Institute of Science (IISc), Bengaluru
[B] S. N. Bose National Centre for Basic Sciences (SNBNCBS), Kolkata
[C] National Chemical Laboratory (NCL), Pune
[D] Centre for Cellular and Molecular Biology (CCMB), Hyderabad
Show Answer
Correct Answer: B [S. N. Bose National Centre for Basic Sciences (SNBNCBS), Kolkata]
Notes:
Researchers at S. N. Bose National Centre for Basic Sciences (SNBNCBS) discovered protein p47’s new role as a “mechanical chaperone.” P47 is a cofactor protein known for assisting p97 in protein trafficking, degradation, and membrane fusion. Study revealed p47 boosts mechanical efficiency of protein extraction from endoplasmic reticulum (ER) to cytoplasm. It stabilizes polypeptides under stress, guides them through pores, prevents misfolding, and improves translocation. This is the first single-molecule evidence of autonomous, force-dependent chaperone-like activity by p47. Discovery opens new therapeutic possibilities for diseases linked to protein instability.
6. Which country has launched EnteroMix, a new mRNA-based cancer vaccine?
[A] Russia
[B] China
[C] India
[D] Australia
Show Answer
Correct Answer: A [Russia]
Notes:
Russia has launched EnteroMix, a new mRNA-based cancer vaccine, reported to show 100 percent efficacy in early trials. It was developed by the National Medical Research Radiology Centre (NMRRC) and Engelhardt Institute of Molecular Biology under the Russian Academy of Sciences. The launch took place at the St Petersburg International Economic Forum (SPIEF 2025) and shared globally via Sputnik news service. The vaccine targets colorectal cancer first, with versions in development for glioblastoma and melanoma. EnteroMix uses four harmless viruses to attack cancer cells and boost immune defence. Russian Federal Medical and Biological Agency (FMBA) confirmed its safety for repeated use and personalised RNA-based tailoring.
7. Which institute has developed cholesterol-based nanomaterials for quantum technologies and spintronic applications?
[A] Indian Institute of Technology, Delhi
[B] Institute of Nano Science and Technology, Mohali
[C] Indian Institute of Technology, Bombay
[D] Tata Institute of Fundamental Research
Show Answer
Correct Answer: B [Institute of Nano Science and Technology, Mohali]
Notes:
Cholesterol, a fat-like substance, can control the spin of electrons, a quantum property crucial for next-generation spintronic devices. Spintronics uses electron spin to develop energy-efficient electronics and bioelectronic devices. Scientists from the Institute of Nano Science and Technology (INST), Mohali, under the Department of Science and Technology (DST), developed cholesterol-based nanomaterials for spintronic and quantum applications. Cholesterol’s intrinsic handedness (chirality) and flexibility allow precise control over molecular properties. This innovation could enable energy-efficient memory chips and greener quantum technologies.
8. What is the name of the asteroid recently confirmed as Earth’s latest quasi-satellite in September 2025?
[A] Victoria 2025
[B] Flora 2025
[C] 2025 PN7
[D] Cardea
Show Answer
Correct Answer: C [2025 PN7]
Notes:
Astronomers discovered asteroid 2025 PN7 in September 2025 as Earth’s latest quasi-satellite. ‘Quasi’ means almost; the asteroid is not gravitationally bound but orbits the Sun in resonance with Earth. It is an Arjuna-class near-Earth asteroid, named after Mahabharata’s Arjuna. 2025 PN7 orbits the Sun while staying close to Earth and will remain in this quasi-satellite state for approx 128 years. It was first spotted on August 2, 2025, by Panoramic Survey Telescope and Rapid Response System 1 (Pan-STARRS 1) in Hawaii.
9. Which institute in Delhi has launched the city’s first central tissue bank for bone grafting in dental surgeries?
[A] All India Institute of Medical Sciences (AIIMS)
[B] Maulana Azad Medical College
[C] Lady Hardinge Medical College
[D] Vardhman Mahavir Medical College
Show Answer
Correct Answer: B [Maulana Azad Medical College]
Notes:
Maulana Azad Medical College (MAMC), Delhi, launched the city’s first Central Tissue Bank for bone grafting in dental surgeries. The facility was inaugurated by Delhi Health Minister Dr Pankaj Kumar Singh. Bone grafting helps reverse jawbone loss and supports dental implants, dentures, and tissue regeneration. The tissue bank provides ready access to high-quality bone and soft tissue grafts, reducing cost and addressing limited availability.
10. Where was India’s first Integrative Oncology Research and Care Centre (IORCC) inaugurated?
[A] Rajasthan
[B] Goa
[C] Maharashtra
[D] Karnataka
Show Answer
Correct Answer: B [Goa]
Notes:
On the 10th National Ayurveda Day, the Ministry of Ayush inaugurated India’s first Integrative Oncology Research and Care Centre (IORCC) at All India Institute of Ayurveda (AIIA), Goa. The IORCC is a first-of-its-kind centre combining Ayurveda, Yoga, Panchakarma, and modern oncology for holistic cancer care. The centre provides patient-centric rehabilitation aimed at reducing side effects, enhancing recovery, and improving quality of life. It is established in collaboration with Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) – Tata Memorial Centre. The facility will act as a hub for research, training, and clinical care in integrative oncology.