1. Indian Astronomical Observatory (IAO), that was recently seen in news, is located in which state/UT?
[A] Lakshadweep
[B] Arunachal Pradesh
[C] Ladakh
[D] Sikkim
Show Answer
Correct Answer: C [Ladakh]
Notes:
Indian astronomers recently photographed interstellar comet C/2025 N1 (ATLAS), also called 3I/ATLAS, using the Himalayan Chandra Telescope (HCT) in Hanle, Ladakh. The telescope is part of the Indian Astronomical Observatory (IAO), also known as Hanle Observatory. Indian Astronomical Observatory (IAO) is located in the Hanle Valley, Ladakh, at 4500 metres above sea level. It was inaugurated in 2001 and is managed by the Indian Institute of Astrophysics (IIA), Bengaluru. The observatory is situated in a dry, cold desert with minimal human interference and clear skies.
2. Which country has created an in vitro biotransformation (ivBT) system that can make sucrose from methanol?
[A] China
[B] India
[C] Japan
[D] Israel
Show Answer
Correct Answer: A [China]
Notes:
Chinese researchers recently created an in vitro biotransformation (ivBT) system that can make sucrose from methanol. Methanol used in the process is produced from industrial waste or carbon dioxide (CO2). This method shows a new way to convert CO2 into food and useful chemicals. It helps in solving environmental problems and food shortages caused by growing population. Biotransformation means changing a substance using biological agents like enzymes. When this change happens outside the living body, it is called in vitro biotransformation (ivBT). The system uses isolated enzymes or cells for the chemical change.
3. AdFalciVax Vaccine, that was recently seen in news, is related to which disease?
[A] Malaria
[B] Polio
[C] Measles
[D] Trachoma
Show Answer
Correct Answer: A [Malaria]
Notes:
The Indian Council of Medical Research (ICMR) is developing a new malaria vaccine called AdFalciVax to fight Plasmodium falciparum. This was recently highlighted due to its unique chimeric and recombinant design. AdFalciVax is being developed with Regional Medical Research Centre Bhubaneswar (RMRCBB), National Institute of Malaria Research (NIMR), and Department of Biotechnology – National Institute of Immunology (DBT-NII). It uses Lactococcus lactis, a safe food-grade bacterium, for production. The vaccine targets both the pre-erythrocytic and sexual stages of the malaria parasite. This dual-target approach offers both personal protection and reduction of mosquito transmission.
4. Lumpy Skin Disease (LSD), that was recently seen in news, is mostly occurred in which species/group?
[A] Birds
[B] Mammals
[C] Cattle
[D] None of the Above
Show Answer
Correct Answer: C [Cattle]
Notes:
Pune district in Maharashtra has been declared an affected area due to rising Lumpy Skin Disease (LSD) cases in cattle. As of now, 906 cattle are infected, with 591 recovered and 15 deaths reported. Pune has over 8.46 lakh cattle as per the 20th Livestock Census and is a major milk producer. Lumpy Skin Disease (LSD) is a highly infectious viral disease affecting all breeds of cattle and water buffalo. It is caused by Lumpy Skin Disease Virus (LSDV), belonging to the genus Capripoxvirus (CaPV) under the family Poxviridae.
5. Which two crops from Ladakh are part of NASA’s Crew-11 experiment on the International Space Station (ISS)?
[A] Barley and maize
[B] Seabuckthorn and Himalayan tartary
[C] Mizuna mustard and Black eyed pea
[D] None of the Above
Show Answer
Correct Answer: B [Seabuckthorn and Himalayan tartary]
Notes:
Seeds of seabuckthorn and Himalayan tartary buckwheat grown in Ladakh’s cold desert are part of NASA’s Crew-11 experiment on the International Space Station (ISS). The seeds were sourced by Indian space start-up Protoplanet based in Bengaluru. The mission launched on August 1, 2025, from Florida and docked at ISS on August 2, 2025. The experiment aims to test how seeds react to space stress and microgravity before germination. It focuses on gene activation and metabolic processes vital for space agriculture. Himalayan tartary buckwheat and seabuckthorn are rich in nutrients and suitable for long-duration space missions.
6. Which organisation has reclassified the Hepatitis D virus (HDV) as carcinogenic to humans?
[A] World Health Organization
[B] United States Department of Health and Human Services
[C] United Nations Development Programme
[D] Doctors Without Borders
Show Answer
Correct Answer: A [World Health Organization]
Notes:
The World Health Organization (WHO) and International Agency for Research on Cancer (IARC) have classified Hepatitis D virus (HDV) as carcinogenic to humans, alongside Hepatitis B (HBV) and Hepatitis C (HCV). HBV, HCV, and HDV infect over 300 million people globally, causing 1.3 million deaths annually from liver cirrhosis and cancer. HDV affects about 5% of chronic HBV patients, mainly in Asia, Africa, Amazon Basin, and high-risk groups like drug users and haemodialysis patients. Co-infection with HBV raises liver cancer risk 2–6 times; 75% may develop cirrhosis within 15 years. No separate HDV vaccine exists; prevention relies on universal HBV vaccination and testing.
7. Where was India’s first ‘Animal Stem Cell Biobank’ inaugurated?
[A] Bengaluru
[B] Chennai
[C] Hyderabad
[D] New Delhi
Show Answer
Correct Answer: C [Hyderabad]
Notes:
Union Minister of State for Science & Technology Jitendra Singh inaugurated India’s first ‘Animal Stem Cell Biobank’ at National Institute of Animal Biotechnology (NIAB), Hyderabad. NIAB is under Department of Biotechnology’s Biotechnology Research Innovation Council (BRIC). The Biobank will store high-quality stem cells from various animal species and supply cost-effective culture media to veterinary clinics, research bodies, and industry.
8. Pneumococcal disease, that was recently seen in news, is caused by which agent?
[A] Virus
[B] Bacteria
[C] Fungus
[D] Protozoa
Show Answer
Correct Answer: B [Bacteria]
Notes:
Pfizer recently launched its 20-valent pneumococcal conjugate vaccine (PCV20) for adults in India. PCV20 protects against 20 serotypes causing most pneumococcal diseases. Pneumococcal disease is caused by the bacterium Streptococcus pneumoniae. It can cause mild infections like ear infections and severe ones like pneumonia, meningitis, and bloodstream infections. Around 90 serotypes exist globally; few cause most diseases. It is a major global health issue, especially affecting young children and the elderly in developing countries.
9. Which company became the first in India to secure the ISCC CORSIA certification for Sustainable Aviation Fuel (SAF)?
[A] Bharat Petroleum Corporation Ltd. (BPCL)
[B] Hindustan Petroleum Corporation Ltd. (HPCL)
[C] Indian Oil Corporation Ltd. (Indian Oil)
[D] None of the Above
Show Answer
Correct Answer: C [Indian Oil Corporation Ltd. (Indian Oil)]
Notes:
Indian Oil Corporation Ltd. (Indian Oil) became the first company in India to secure International Sustainability & Carbon Certification (ISCC) CORSIA for Sustainable Aviation Fuel (SAF) at its Panipat Refinery. The certification is mandatory for commercial SAF production and aligns India with global aviation fuel standards. Certificate was handed over by Cotecna to Indian Oil Chairman A.S. Sahney in New Delhi. ISCC CORSIA, developed under Carbon Offsetting and Reduction Scheme for International Aviation (CORSIA) of International Civil Aviation Organization (ICAO), ensures sustainability and lifecycle carbon standards.
10. Rubella disease, that was recently seen in news, is caused by which agent?
[A] Bacteria
[B] Virus
[C] Fungus
[D] Protozoa
Show Answer
Correct Answer: B [Virus]
Notes:
The World Health Organization (WHO) recently announced that Nepal has eliminated rubella as a public health problem. Rubella, also called German measles or three-day measles, is a contagious viral infection known for its red rash. It is caused by the Rubella virus, a single-stranded RNA virus, different from the measles virus. Rubella spreads through coughing, sneezing, contaminated surfaces, and from mother to fetus during pregnancy. This can lead to fetal death or Congenital Rubella Syndrome (CRS), causing hearing loss, eye and heart defects, autism, diabetes mellitus, and thyroid problems.