1. Which institutions recently created the world’s first entirely AI-generated genome?
[A] California Institute of Technology and Harvard University
[B] Massachusetts Institute of Technology (MIT) and University of Oxford
[C] Harvard University and University of Cambridge
[D] Stanford University and the Arc Institute
Show Answer
Correct Answer: D [Stanford University and the Arc Institute]
Notes:
Researchers at Stanford University and the Arc Institute created the world’s first entirely AI-generated genome. The AI-designed virus can infect and kill bacteria, acting as a bacteriophage. Artificial Intelligence (AI) model named Evo was used, employing genome “language models” to design complete viral genomes. Evo was trained on about 2 million viral genomes to learn DNA patterns, gene order, and composition. Scientists guided Evo to mimic phiX174, a small bacteriophage with 11 genes and approximately 5,000 DNA letters. This achievement marks a significant advancement beyond AI-designed proteins or small multi-gene systems. It demonstrates AI’s potential to innovate in synthetic biology and genome engineering.
2. Infectious Bovine Rhinotracheitis (IBR) disease, that was recently seen in news, is caused by which agent?
[A] Bacteria
[B] Virus
[C] Fungus
[D] Protozoa
Show Answer
Correct Answer: B [Virus]
Notes:
Indian Immunologicals Limited (IIL) has launched India’s first indigenously developed glycoprotein E (gE) deleted DIVA (Differentiated between Infected and Vaccinated Animal) marker vaccine against Infectious Bovine Rhinotracheitis (IBR) in Anand, Gujarat. IBR is caused by Bovine Herpes Virus-1 (BHV-1), belonging to the genus Varicellovirus under Alphaherpesvirinae subfamily. It mainly affects domestic and wild cattle. The disease has three forms – respiratory, genital and encephalitic, with respiratory and genital being common. Transmission occurs through aerosols and semen from bulls to milch animals, impacting the reproductive system.
3. Which space organization has launched the Interstellar Mapping and Acceleration Probe (IMAP) mission?
[A] Japan Aerospace Exploration Agency (JAXA)
[B] National Aeronautics and Space Administration (NASA)
[C] European Space Agency (ESA)
[D] Indian Space Research Organisation (ISRO)
Show Answer
Correct Answer: B [National Aeronautics and Space Administration (NASA)]
Notes:
National Aeronautics and Space Administration (NASA) has recently launched the Interstellar Mapping and Acceleration Probe (IMAP) mission. Its main goal is to study how solar particles are energised and how the heliosphere shields Earth. Heliosphere is a giant bubble formed by the Sun’s solar wind that covers the entire solar system. Interstellar Mapping and Acceleration Probe (IMAP) will map the heliosphere’s boundary, trace energetic particles, and improve space weather forecasting. It is positioned at the first Earth-Sun Lagrange Point (L1), about 1 million miles from Earth towards the Sun. It will provide near real-time data on solar wind and energetic particles to monitor space weather hazards.
4. Lecanemab drug, that was recently seen in news, is used to treat which disease?
[A] Multiple Sclerosis
[B] Tuberculosis
[C] Alzheimer’s Disease
[D] Huntington’s Disease
Show Answer
Correct Answer: C [Alzheimer’s Disease]
Notes:
Australia recently approved Lecanemab for early-stage Alzheimer’s disease. Dementia causes progressive memory and thinking problems and is now Australia’s leading cause of death. Alzheimer’s disease accounts for 60-80% of dementia cases. Lecanemab is a monoclonal antibody drug that targets amyloid proteins in the brain. It aims to slow disease progression by tackling the cause of Alzheimer’s, not just symptoms. The drug works by using antibodies to mark amyloid for removal by brain immune cells, preventing toxicity to brain cells.
5. Which institution has launched a tool called “SARAL” to make scientific research more accessible?
[A] Anusandhan National Research Foundation (ANRF)
[B] Council of Scientific & Industrial Research (CSIR)
[C] NITI Aayog
[D] Ministry of Skill Development
Show Answer
Correct Answer: A [Anusandhan National Research Foundation (ANRF)]
Notes:
The Anusandhan National Research Foundation (ANRF) launched SARAL (Simplified and Automated Research Amplification and Learning) to make research easy and accessible. SARAL uses Artificial Intelligence (AI) to simplify complex research into videos, podcasts, posters, and presentations. Anusandhan National Research Foundation (ANRF) aims to harness deep science and engineering to build deep tech products and start-ups. It is developing an AI Science and Engineering Open India Stack for drug discovery, aerospace design, climate studies, and advanced materials.
6. Which cities in India have been selected by Meta Platforms as landing sites for the undersea cable project, Waterworth?
[A] Mumbai and Chennai
[B] Chennai and Kolkata
[C] Mumbai and Visakhapatnam
[D] Visakhapatnam and Kochi
Show Answer
Correct Answer: C [Mumbai and Visakhapatnam]
Notes:
Meta Platforms has chosen Mumbai and Visakhapatnam as landing sites for its undersea cable project named Waterworth. Undersea cables are fiber-optic cables laid on the ocean floor to transmit information globally. They form the backbone of the international internet. Around 90% of global data and 80% of world trade are carried through undersea cables. They also facilitate approximately $10 trillion of financial transactions annually. The project will strengthen India’s connectivity with global digital networks and support faster internet and data services.
7. Fibromyalgia, that was recently seen in news, is a chronic health condition that primarily affects which part of the human body?
[A] Bones
[B] Muscles and soft tissues
[C] Heart and lungs
[D] Kidneys and liver
Show Answer
Correct Answer: B [Muscles and soft tissues]
Notes:
Fibromyalgia is a real, chronic health condition affecting 2–3% of the global population. It causes long-term pain and tenderness in muscles and soft tissues. Common symptoms include fatigue, sleep disturbances, memory issues, stress, anxiety, and depression. The exact cause is unknown, but affected individuals have heightened sensitivity to pain. Symptoms often appear in flare-ups that come and go. Other symptoms include headaches, migraines, digestive issues, restless leg syndrome, and temporomandibular jaw disorders. There is no cure, but treatment helps control symptoms.
8. What is “Bordetella holmesii” that was recently seen in news?
[A] Bacteria
[B] Invasive weed
[C] Butterfly
[D] Fungus
Show Answer
Correct Answer: A [Bacteria]
Notes:
The Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh has reported a sharp rise in infections caused by Bacterium Bordetella holmesii in North India. This bacterium mimics whooping cough (pertussis), making diagnosis difficult. Bordetella holmesii was first identified in 1995. It is a gram-negative coccobacillus capable of causing pertussis-like respiratory illness. Besides cough infections, it can cause endocarditis, pneumonia, cellulitis, arthritis, and pyelonephritis. The recent surge highlights the need for improved diagnostic tests and public health awareness to differentiate it from regular whooping cough infections.
9. Which rocket was used by ISRO to successfully launch India’s heaviest communication satellite CMS-03?
[A] PSLV-C58
[B] GSLV Mk II
[C] LVM3-M5
[D] SSLV-D2
Show Answer
Correct Answer: C [LVM3-M5]
Notes:
The Indian Space Research Organisation (ISRO) successfully launched the LVM3-M5 rocket from Satish Dhawan Space Centre, Sriharikota at 5:35 pm. The rocket carried CMS-03, India’s heaviest communication satellite weighing 4,400 kilograms. It was the fifth operational flight of the Launch Vehicle Mark-3 (LVM3) launcher. CMS-03 was launched into a Geosynchronous Transfer Orbit (GTO). The satellite will provide multi-band communication services across India and nearby ocean regions. It will enhance secure data, voice, and video connectivity for civilian and strategic applications. The mission highlights India’s capability in heavy satellite launches and strengthens its communication network.
10. Which country has become the eighth country in the world to introduce the Typhoid Conjugate Vaccine (TCV) into its immunisation programme?
[A] Sri Lanka
[B] Myanmar
[C] Bangladesh
[D] Nepal
Show Answer
Correct Answer: C [Bangladesh]
Notes:
Bangladesh became the 8th country in the world to introduce the Typhoid Conjugate Vaccine (TCV) in its routine immunisation programme. Around 50 million children aged 9 months to 15 years will receive the vaccine under a nationwide campaign. India is the major vaccine supplier for this drive but has not yet included TCV in its Universal Immunisation Programme (UIP). Typhoid fever is caused by the Salmonella typhi bacterium and spreads through contaminated food and water or vectors like flies. The disease can lead to fever lasting several weeks, and complications like intestinal perforation can cause death. The World Health Organization (WHO) estimates 9–12 million global typhoid cases and over 1 lakh deaths annually — with India, Bangladesh, and Pakistan as hotspots