1. Which district in Gujarat has been identified as a Mars-analogue site due to the presence of jarosite deposits?
[A] Banaskantha
[B] Junagadh
[C] Kutch
[D] Bhavnagar
Show Answer
Correct Answer: C [Kutch]
Notes:
Matanomadh, a remote village in Kutch district, Gujarat, may serve as a test bed for ISRO’s Mangalyaan-2 mission to Mars. Researchers from Space Applications Centre (SAC) Ahmedabad, Savitribai Phule Pune University (SPPU), and Birbal Sahni Institute of Palaeosciences, Lucknow dated jarosite mineral in Matanomadh to 55 million years (Paleocene period). Jarosite is a yellow, iron-rich sulphate mineral, similar to those found on Mars, indicating past water activity. The site allows field-analogue studies for Mars, including rover testing, drilling, geochemistry, and astrobiology research. The discovery can help decode Martian geology, past chemical interactions, and organic molecule trapping, aiding future Mars missions.
2. Which institute discovered that protein p47 acts as a “mechanical chaperone”, enhancing protein stability under mechanical stress?
[A] Indian Institute of Science (IISc), Bengaluru
[B] S. N. Bose National Centre for Basic Sciences (SNBNCBS), Kolkata
[C] National Chemical Laboratory (NCL), Pune
[D] Centre for Cellular and Molecular Biology (CCMB), Hyderabad
Show Answer
Correct Answer: B [S. N. Bose National Centre for Basic Sciences (SNBNCBS), Kolkata]
Notes:
Researchers at S. N. Bose National Centre for Basic Sciences (SNBNCBS) discovered protein p47’s new role as a “mechanical chaperone.” P47 is a cofactor protein known for assisting p97 in protein trafficking, degradation, and membrane fusion. Study revealed p47 boosts mechanical efficiency of protein extraction from endoplasmic reticulum (ER) to cytoplasm. It stabilizes polypeptides under stress, guides them through pores, prevents misfolding, and improves translocation. This is the first single-molecule evidence of autonomous, force-dependent chaperone-like activity by p47. Discovery opens new therapeutic possibilities for diseases linked to protein instability.
3. Which country has launched EnteroMix, a new mRNA-based cancer vaccine?
[A] Russia
[B] China
[C] India
[D] Australia
Show Answer
Correct Answer: A [Russia]
Notes:
Russia has launched EnteroMix, a new mRNA-based cancer vaccine, reported to show 100 percent efficacy in early trials. It was developed by the National Medical Research Radiology Centre (NMRRC) and Engelhardt Institute of Molecular Biology under the Russian Academy of Sciences. The launch took place at the St Petersburg International Economic Forum (SPIEF 2025) and shared globally via Sputnik news service. The vaccine targets colorectal cancer first, with versions in development for glioblastoma and melanoma. EnteroMix uses four harmless viruses to attack cancer cells and boost immune defence. Russian Federal Medical and Biological Agency (FMBA) confirmed its safety for repeated use and personalised RNA-based tailoring.
4. Which Indian research institute developed a multifunctional wound-healing pad using the red ivy plant (Strobilanthes alternata)?
[A] Indian Institute of Science (IISc), Bengaluru
[B] Jawaharlal Nehru Tropical Botanic Garden & Research Institute, Thiruvananthapuram
[C] National Botanical Research Institute (NBRI), Lucknow
[D] Indian Agricultural Research Institute (IARI), New Delhi
Show Answer
Correct Answer: B [Jawaharlal Nehru Tropical Botanic Garden & Research Institute, Thiruvananthapuram]
Notes:
Researchers at Jawaharlal Nehru Tropical Botanic Garden & Research Institute (JNTBGRI), Palode, Thiruvananthapuram, developed a multifunctional wound-healing pad. The pad is based on the red ivy plant, locally called murikooti pacha, scientifically Strobilanthes alternata of the Acanthaceae family. Scientists at the Centre of Excellence in Phytochemical Nanotechnology of JNTBGRI isolated a new molecule, acteoside, from red ivy for the first time. Acteoside shows high efficacy even at 0.2% concentration and is the key ingredient in the pad. The pad uses electro-spun nanofiber layers made from biodegradable, non-toxic, FDA-approved polymers. Red ivy has long been used in traditional medicine for treating cuts and wounds.
5. Which garden was inaugurated in Lucknow at the National Botanical Research Institute (NBRI) during the CSIR Startup Conclave?
[A] Rose Garden
[B] Swastik Lotus Garden
[C] Mughal Garden
[D] Herbal Medicinal Garden
Show Answer
Correct Answer: B [Swastik Lotus Garden]
Notes:
Recently, the first-of-its-kind Swastik Lotus Garden was inaugurated at the National Botanical Research Institute (NBRI), Lucknow, during the CSIR Startup Conclave. The garden features 60 lotus varieties from across the world and 50 species of water lilies. Conservation is ensured through advanced genetic methods, light regulation, and scientific treatments. CSIR technologies were transferred to private companies for public access, including perfumes Frotus-Rudra, Frotus-Kumbh, air-freshener Frotus Fresh, green firecrackers, aromatherapy oil Relaxomap, and portable water analysis kits. The initiative strengthens scientific innovation, conservation, and entrepreneurship at grassroots and national levels.
6. Hand, Foot, and Mouth Disease (HFMD), that was recently seen in news, is caused by which agent?
[A] Bacteria
[B] Virus
[C] Fungus
[D] Protozoa
Show Answer
Correct Answer: B [Virus]
Notes:
A viral infection called Hand, Foot, and Mouth Disease (HFMD) is spreading rapidly among children in Delhi and Haryana, prompting advisories. It is a highly contagious illness caused by a virus. It causes blister-like rashes on hands and feet, painful mouth sores, and sometimes rashes on chest, back, arms, legs, genitals, and buttocks. It mostly affects infants and children under 5 years, spreading quickly in schools and daycare. It is different from foot-and-mouth disease in animals, caused by a different virus. Transmission happens through unwashed hands, saliva, mucus, feces, or blister fluid. No cure or vaccine exists; recovery usually takes 7–10 days with basic care. Complications are rare, but children under 2 may take longer to recover.
7. Which institutions recently created the world’s first entirely AI-generated genome?
[A] California Institute of Technology and Harvard University
[B] Massachusetts Institute of Technology (MIT) and University of Oxford
[C] Harvard University and University of Cambridge
[D] Stanford University and the Arc Institute
Show Answer
Correct Answer: D [Stanford University and the Arc Institute]
Notes:
Researchers at Stanford University and the Arc Institute created the world’s first entirely AI-generated genome. The AI-designed virus can infect and kill bacteria, acting as a bacteriophage. Artificial Intelligence (AI) model named Evo was used, employing genome “language models” to design complete viral genomes. Evo was trained on about 2 million viral genomes to learn DNA patterns, gene order, and composition. Scientists guided Evo to mimic phiX174, a small bacteriophage with 11 genes and approximately 5,000 DNA letters. This achievement marks a significant advancement beyond AI-designed proteins or small multi-gene systems. It demonstrates AI’s potential to innovate in synthetic biology and genome engineering.
8. Which institute conducted the first successful wheat cultivation experiment in the Thar desert using ‘soilification’ technology?
[A] Banaras Hindu University
[B] Punjab Agricultural University
[C] Central Soil Salinity Research Institute
[D] Central University of Rajasthan
Show Answer
Correct Answer: D [Central University of Rajasthan]
Notes:
Recently, Central University of Rajasthan (CUoR) conducted the first successful wheat cultivation in arid land using desert ‘soilification’ technology. The experiment aims to stop the expansion of western Rajasthan’s Thar desert towards the National Capital Region. Desert sand was converted into soil using polymers and indigenous bioformulation, enhancing water retention and soil structure. The project was supported by Krishi Vigyan Kendra (KVK) and the State Horticulture Department. The experiment proves that even barren desert land can become productive with biotechnology.
9. Which Indian institute has developed the new siphon-based thermal desalination system?
[A] Indian Institute of Science (IISc)
[B] Indian Institute of Technology, Madras
[C] CSIR – National Chemical Laboratory (NCL)
[D] Indian Institute of Technology, Bombay
Show Answer
Correct Answer: A [Indian Institute of Science (IISc)]
Notes:
Indian Institute of Science (IISc) has developed a new siphon-based thermal desalination system for clean drinking water. Traditional solar stills face salt buildup and scaling limits restricting output. The system uses a composite siphon of fabric wick and grooved metallic surface to draw water and flush out salt before crystallization. It is low-cost, scalable, and sustainable, made from aluminum and fabric, powered by solar or waste heat. It is useful for off-grid areas, disaster zones, coastal and island communities facing water stress.
10. What is the primary objective of NASA’s Cassini mission?
[A] To study Jupiter’s atmosphere
[B] To explore Saturn and its moons
[C] To map the surface of Mars
[D] To study Moon’s atmosphere
Show Answer
Correct Answer: B [To explore Saturn and its moons]
Notes:
A new analysis of NASA’s Cassini spacecraft data shows that Saturn’s moon Enceladus may support life. Cassini was a joint mission of NASA, European Space Agency (ESA), and Italian Space Agency (ASI). It was launched on October 15, 1997, to study Saturn and its moons in detail. The mission had NASA’s Cassini orbiter and ESA’s Huygens probe, which landed on Titan, Saturn’s largest moon. Cassini studied Saturn’s atmosphere, rings, and magnetosphere, along with Titan’s surface and atmosphere. It provided key insights into Saturn’s cloud properties, ring composition, and planetary evolution.