1. Rotovac vaccine, that was recently seen in news, is used for the prevention/treatment of which disease?
[A] Measles
[B] Tuberculosis
[C] Rotavirus
[D] Polio
Show Answer
Correct Answer: C [Rotavirus]
Notes:
A recent study found that the indigenous rotavirus vaccine ‘Rotavac’ is as effective in real-world use as in clinical trials. Rotavac is an oral, live attenuated, monovalent liquid vaccine against rotavirus. It was developed through a public-private partnership involving the Department of Biotechnology (DBT), Bharat Biotech, and the U.S. National Institutes of Health (NIH). Rotavirus is a viral disease that commonly causes diarrhoeal illness in children. There is no specific medicine to treat rotavirus infection, and vaccination provides the best protection. This study highlights Rotavac’s continued role in child health.
2. Which country has developed the MAM01 monoclonal antibody that showed strong protection against malaria?
[A] China
[B] Japan
[C] United States
[D] India
Show Answer
Correct Answer: C [United States]
Notes:
United States (US) researchers have developed a novel monoclonal antibody named MAM01 that showed strong protection against malaria in an early clinical trial. MAM01 targets a highly conserved region of Plasmodium falciparum circumsporozoite protein, blocking infection before the parasite enters the bloodstream. The trial demonstrated dose-dependent full protection with minimal side effects. It is administered as a single long-acting injection, providing immediate and months-long protection. Monoclonal antibodies (mAbs) are lab-made proteins mimicking the body’s natural immune defenses.
3. Which country has successfully tested its new atomic-powered and nuclear-capable underwater drone named Poseidon?
[A] Russia
[B] China
[C] Australia
[D] Japan
Show Answer
Correct Answer: A [Russia]
Notes:
Russia has successfully tested its new atomic-powered and nuclear-capable underwater drone named Poseidon. President Vladimir Putin announced the test, calling it a major success and saying it cannot be intercepted. The test took place just days after Russia also tested the Burevestnik nuclear-powered cruise missile. Both tests are seen as signals to the United States amid the ongoing Ukraine conflict. The Poseidon drone was tested using nuclear power for the first time. It reportedly surpasses all current systems in speed and depth. Its nuclear reactor is 100 times smaller than those on submarines. The drone’s nuclear warhead is said to be more powerful than the Sarmat Intercontinental Ballistic Missile (ICBM).
4. Scrub Typhus, that was recently seen in news, is caused by which microorganism?
[A] Bacteria
[B] Virus
[C] Fungus
[D] Protozoa
Show Answer
Correct Answer: A [Bacteria]
Notes:
A Gulf Keralite’s quick return home for fever treatment proved life-saving after he was diagnosed with scrub typhus. Scrub Typhus is an infectious disease caused by the bacteria Orientia tsutsugamushi. It spreads through bites of infected chiggers (young mites) and not from person to person. Its prevalence depends on factors like climate, vector abundance, farming, domestic animals, and sanitation. The disease is more common during cooler months.
5. Which institute recently initiated research on the Cycad plant due to concerns about a potential neurotoxin?
[A] Indian Institute of Science (IISc), Bengaluru
[B] All India Institute of Medical Sciences (AIIMS), Bhubaneswar
[C] National Botanical Research Institute (NBRI), Lucknow
[D] Indian Council of Medical Research (ICMR), New Delhi
Show Answer
Correct Answer: B [All India Institute of Medical Sciences (AIIMS), Bhubaneswar]
Notes:
AIIMS Bhubaneswar has started research on the Cycad plant due to the presence of BMAA (β-N-methylamino-L-alanine), a possible neurotoxin. Cycads are palmlike, woody gymnosperm plants. They are ancient species that existed alongside dinosaurs for over 300 million years. They grow in various habitats, from wet rainforests and grasslands to semidesert and seasonally dry forests. Their distribution spans tropical and subtropical regions, including the Americas, Caribbean, sub-Saharan Africa, Madagascar, eastern India, China, Japan, Southeast Asia, Oceania, and Australia.
6. Where is India’s first 3 Megawatt-hour (MWh) Vanadium Redox Flow Battery system installed?
[A] Greater Noida
[B] Chennai
[C] Hyderabad
[D] Bengaluru
Show Answer
Correct Answer: A [Greater Noida]
Notes:
Shri Manohar Lal, Minister of Power and Housing & Urban Affairs, inaugurated India’s first and largest Vanadium Redox Flow Battery (VRFB) system. The VRFB has a capacity of 3 Megawatt-hour (MWh) at NTPC’s NETRA Research & Development Centre in Greater Noida. This milestone advances India’s long-duration energy storage (LDES) solutions and strengthens renewable energy integration and national grid resilience. Vanadium Redox Flow Battery (VRFB) is a modern technology offering an alternative to lithium-ion batteries, expanding the pool of usable elements for battery systems.
7. Sentinel-6B is a joint mission of which agencies?
[A] NASA, National Oceanic and Atmospheric Administration (NOAA), and European Space Agency (ESA)
[B] National Oceanic and Atmospheric Administration (NOAA) and Indian Space Research Organisation (ISRO)
[C] European Space Agency (ESA) and China National Space Administration (CNSA)
[D] Japan Aerospace Exploration Agency (JAXA) and Indian Space Research Organisation (ISRO)
Show Answer
Correct Answer: A [NASA, National Oceanic and Atmospheric Administration (NOAA), and European Space Agency (ESA)]
Notes:
Sentinel-6B was recently launched from Vandenberg Space Force Base, California, marking a major step in global ocean monitoring. It is a joint mission of NASA, National Oceanic and Atmospheric Administration (NOAA), and European Space Agency (ESA). It will track rising sea levels and their impacts, continuing the work of Sentinel-6 Michael Freilich launched in 2020. It orbits Earth at 7.2 km per second, completing one revolution in 112 minutes. It will measure sea levels with accuracy up to one inch, covering over 90% of oceans. Its mission life is 5.5 years. It carries six science instruments and uses fixed plus deployable solar panels in a non-Sun-synchronous orbit
8. What is the name of India’s first indigenous CRISPR-based gene therapy for Sickle Cell Disease?
[A] SCD-CURE
[B] GEN-EDIT 1
[C] BIRSA 101
[D] HematoGene
Show Answer
Correct Answer: C [BIRSA 101]
Notes:
India’s first indigenous CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-based gene therapy for Sickle Cell Disease (SCD), named BIRSA 101, was recently launched by the Union Minister of State (Independent Charge) for Science & Technology. It is developed by CSIR (Council of Scientific and Industrial Research) – Institute of Genomics and Integrative Biology (IGIB). BIRSA 101 uses CRISPR-Cas9 gene-editing technology to precisely correct the genetic mutation causing SCD. The therapy is administered as a one-time infusion, after which the body produces normal red blood cells instead of sickle-shaped ones.
9. Which institution recently discovered a new deep-sea squid species named Taningia silasii?
[A] National Institute of Ocean Technology (NIOT)
[B] Central Marine Fisheries Research Institute (CMFRI), Kochi
[C] Indian National Centre for Ocean Information Services (INCOIS)
[D] Zoological Survey of India (ZSI)
Show Answer
Correct Answer: B [Central Marine Fisheries Research Institute (CMFRI), Kochi]
Notes:
Recently, researchers from the Central Marine Fisheries Research Institute (CMFRI), Kochi discovered a new deep-sea squid species in the Arabian Sea and named it Taningia silasii (Indian octopus squid). The species was found at a depth of nearly 390 metres off the Kollam coast. It belongs to the family Octopoteuthidae. It is only the second formally recognised species in the Taningia genus. The first species in this genus was Taningia danae, earlier found in the Atlantic Ocean.
10. What is the name of India’s first private commercial orbital rocket unveiled by Skyroot Aerospace?
[A] Agni-I
[B] Gaganyaan
[C] Aditya-I
[D] Vikram-I
Show Answer
Correct Answer: D [Vikram-I]
Notes:
Skyroot Aerospace inaugurated its Infinity Campus in Hyderabad and virtually unveiled Vikram-I, India’s first private commercial orbital rocket. Vikram-I is capable of placing satellites into Earth orbit. This launch marks a major milestone for India’s growing private space sector. The private space sector in India was opened to entrepreneurs three years ago. The development highlights rising startup participation in advanced space technology. It reflects India’s shift toward innovation-driven and private-led space missions.