1. Fibromyalgia, that was recently seen in news, is a chronic health condition that primarily affects which part of the human body?
[A] Bones
[B] Muscles and soft tissues
[C] Heart and lungs
[D] Kidneys and liver
Show Answer
Correct Answer: B [Muscles and soft tissues]
Notes:
Fibromyalgia is a real, chronic health condition affecting 2–3% of the global population. It causes long-term pain and tenderness in muscles and soft tissues. Common symptoms include fatigue, sleep disturbances, memory issues, stress, anxiety, and depression. The exact cause is unknown, but affected individuals have heightened sensitivity to pain. Symptoms often appear in flare-ups that come and go. Other symptoms include headaches, migraines, digestive issues, restless leg syndrome, and temporomandibular jaw disorders. There is no cure, but treatment helps control symptoms.
2. In October 2025, Mounjaro became India’s top-selling drug by value, overtaking which antibiotic?
[A] Amoxicillin
[B] Augmentin
[C] Doxycyclin
[D] Azithromycin
Show Answer
Correct Answer: B [Augmentin]
Notes:
Eli Lilly’s weight-loss drug Mounjaro became India’s top-selling drug by value in October 2025. It overtook GlaxoSmithKline’s (GSK) Augmentin, a widely used antibiotic. Mounjaro earned ₹1 billion ($11.38 million) in October, while Augmentin made ₹800 million. By volume, Augmentin sold 5,784 units, whereas Mounjaro sold only 85 units due to its high price. Mounjaro helps control blood sugar and slow digestion and belongs to the GLP-1 receptor agonist class used for obesity and diabetes. It was launched in India in March 2025 and has earned ₹3.33 billion till October. Mounjaro’s consumption was 10 times higher than rival Wegovy by Novo Nordisk, launched in June 2025. Eli Lilly sold 262,000 units, while Novo Nordisk sold 26,000 units in October.
3. Batten disease, that was recently seen in news, primarily affects which part of the human body?
[A] Heart
[B] Lungs
[C] Kidneys
[D] Brain
Show Answer
Correct Answer: D [Brain]
Notes:
Recently, researchers found that male and female brains respond differently as Batten Disease progresses, opening new paths for treatment. Batten Disease is a rare genetic disorder affecting the brain and nervous system. It is congenital, progressive, and terminal, leading to steady decline in nervous system function. Symptoms include loss of vision and seizures, beginning in infancy, childhood, or rarely adulthood. Life expectancy varies from early childhood to the twenties depending on the form.
4. The Visible Emission Line Coronagraph (VELC) is the primary payload of which Indian space mission?
[A] Chandrayaan-3
[B] Chandrayaan-2
[C] Mangalyaan-2
[D] Aditya-L1
Show Answer
Correct Answer: D [Aditya-L1]
Notes:
In November 2025, scientists from the Indian Institute of Astrophysics (IIA) collaborated with the National Aeronautics and Space Administration (NASA) to estimate key parameters of a Coronal Mass Ejection (CME). They used data from the Visible Emission Line Coronagraph (VELC) payload onboard India’s Aditya-L1 mission. VELC is the main payload of Aditya-L1, India’s first solar observatory placed 1.5 million kilometres from Earth. It is an internally occulted solar coronagraph capable of imaging, spectroscopy, and spectro-polarimetry near the solar limb.
5. Where is India’s first 3 Megawatt-hour (MWh) Vanadium Redox Flow Battery system installed?
[A] Greater Noida
[B] Chennai
[C] Hyderabad
[D] Bengaluru
Show Answer
Correct Answer: A [Greater Noida]
Notes:
Shri Manohar Lal, Minister of Power and Housing & Urban Affairs, inaugurated India’s first and largest Vanadium Redox Flow Battery (VRFB) system. The VRFB has a capacity of 3 Megawatt-hour (MWh) at NTPC’s NETRA Research & Development Centre in Greater Noida. This milestone advances India’s long-duration energy storage (LDES) solutions and strengthens renewable energy integration and national grid resilience. Vanadium Redox Flow Battery (VRFB) is a modern technology offering an alternative to lithium-ion batteries, expanding the pool of usable elements for battery systems.
6. Motor Neuron Disease (MND), that was recently seen in news, primarily affects which part of the human body?
[A] Circulatory system
[B] Nervous system
[C] Digestive system
[D] Endocrine system
Show Answer
Correct Answer: B [Nervous system]
Notes:
Scientists have recently developed a breakthrough therapy that clears toxic proteins from nerve cells, offering new hope for treating Motor Neuron Disease (MND). Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig’s Disease, is a rare condition that damages parts of the nervous system. It causes muscle weakness, wasting, and paralysis as motor neurons in the brain and spinal cord die prematurely, stopping signals between the brain and muscles. Around 20% of cases are genetic, mostly affecting people over 50 years old. There is currently no cure, but treatment helps manage symptoms.
7. What is the name of India’s first indigenous CRISPR-based gene therapy for Sickle Cell Disease?
[A] SCD-CURE
[B] GEN-EDIT 1
[C] BIRSA 101
[D] HematoGene
Show Answer
Correct Answer: C [BIRSA 101]
Notes:
India’s first indigenous CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-based gene therapy for Sickle Cell Disease (SCD), named BIRSA 101, was recently launched by the Union Minister of State (Independent Charge) for Science & Technology. It is developed by CSIR (Council of Scientific and Industrial Research) – Institute of Genomics and Integrative Biology (IGIB). BIRSA 101 uses CRISPR-Cas9 gene-editing technology to precisely correct the genetic mutation causing SCD. The therapy is administered as a one-time infusion, after which the body produces normal red blood cells instead of sickle-shaped ones.
8. Which organizations have indigenously built the India’s first private PSLV rocket?
[A] Hindustan Aeronautics Limited and L&T – Larsen & Toubro
[B] Defence Research and Development Organisation and Tata Group
[C] Indian Space Research Organisation and BHEL – Bharat Heavy Electricals Limited
[D] Bharat Electronics Limited and Defence Research and Development Organisation
Show Answer
Correct Answer: A [Hindustan Aeronautics Limited and L&T – Larsen & Toubro]
Notes:
The Hindustan Aeronautics Limited (HAL)–Larsen & Toubro (L&T) consortium has indigenously built India’s first private Polar Satellite Launch Vehicle (PSLV). The PSLV is scheduled to launch the Oceansat satellite early next year. India’s Indian Space Research Organisation (ISRO) signed a 2022 contract with the HAL–L&T consortium for end-to-end production of five PSLV-XL rockets. This move shifts PSLV manufacturing from ISRO to industry partners while ISRO focuses on new missions and research. The consortium has faced production challenges, resolved with ISRO’s support. HAL also received technology for the Small Satellite Launch Vehicle (SSLV) to fully own and operate its production.
9. Where was India’s first single-use bioprocess design and scale-up facility inaugurated in November 2025?
[A] Bengaluru
[B] Kolkata
[C] Hyderabad
[D] Chennai
Show Answer
Correct Answer: C [Hyderabad]
Notes:
Telangana’s 1 Bio, India’s first single-use bioprocess design and scale-up facility, was inaugurated at Genome Valley, Hyderabad. It was created to solve the lack of affordable bioprocess scale-up infrastructure despite Telangana’s strong biotech talent. The facility supports start-ups and big companies with end-to-end process development and pilot validation. It was developed by the Government of Telangana, Telangana Lifesciences, Department of Biotechnology (DBT), Government of India, and Telangana Industrial Infrastructure Corporation (TGIIC). It has 500-litre bioreactors, advanced processing systems, and analytical labs.
10. What is the name of India’s first solar observatory mission launched to study the Sun?
[A] Chandrayaan-3
[B] Aditya-L1
[C] Astrosat
[D] NISAR
Show Answer
Correct Answer: B [Aditya-L1]
Notes:
Aditya-L1, India’s first solar observatory, helped scientists understand why the May 2024 solar storm — the strongest in 20+ years — behaved unusually. A solar storm is a sudden burst of particles, energy, magnetic fields, and solar material ejected by the Sun. It is caused when the Sun’s twisted magnetic fields become overstretched and snap in a magnetic reconnection, releasing huge energy. Solar storms can produce a solar flare, radiation storm, or a coronal mass ejection (CME).