U.S.-based biotech company Colossal Biosciences announced the birth of three genetically engineered wolf pups, aiming to revive the extinct dire wolf species after 12,500 years. This marks the first-ever attempt at “de-extinction,” using methods like gene editing (e.g., CRISPR-Cas9), ancient DNA sequencing, cloning, and synthetic biology. De-extinction helps in biodiversity conservation, ecological balance, and climate resilience, and boosts public interest in conservation science. The dire wolf, scientifically named Aenocyon dirus, once lived in North American grasslands and forests during the Pleistocene Epoch and went extinct around 12,500 years ago.
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