Labrys portucalensis F11

January 30, 2025

Recent studies have revealed a promising bacterial strain that can degrade per- and polyfluoroalkyl substances (PFAS). Commonly referred to as “forever chemicals,” Researchers from the University at Buffalo have identified Labrys portucalensis F11 (F11), a bacterial strain capable of breaking down these hazardous substances effectively.

About PFAS and Their Impact

PFAS have been in use since the 1950s.
They are found in various products such as nonstick cookware and firefighting foams.
Their strong carbon-fluorine bonds make them resistant to natural degradation processes.
This persistence raises environmental and health concerns, as they can accumulate in water and soil.

Discovery of Labrys portucalensis F11

The F11 strain was isolated from contaminated soil in Portugal. It has shown the ability to metabolise harmful contaminants, including pharmaceuticals. However, its potential to degrade PFAS was previously unexplored. Tests revealed that F11 could degrade over 90% of perfluorooctane sulfonic acid (PFOS) within 100 days.

Mechanism of Action

F11 operates by cleaving carbon-fluorine bonds. Researchers discovered that F11 not only breaks down PFOS but also removes fluorine from smaller byproducts. This dual action is crucial for effective PFAS degradation. Elevated fluoride levels in samples confirmed the successful cleavage of these bonds.

Testing and Results

The research involved incubating F11 in sealed flasks with PFAS as the only carbon source. Over various periods, F11 demonstrated degradation capabilities. In addition to PFOS, it also degraded 58% of 5:3 fluorotelomer carboxylic acid and 21% of 6:2 fluorotelomer sulfonate.

Challenges and Future Directions

Despite its capabilities, F11 requires lengthy exposure times for substantial degradation. The current testing environment lacked competing carbon sources, which may not reflect natural conditions. Future research aims to optimise the bacterial process while providing sufficient nutrients to maintain F11’s focus on PFAS degradation.

Potential Applications

F11 holds promise for bioaugmentation strategies. This involves introducing the bacteria into contaminated sites or wastewater treatment systems. Implementing F11 in treatment plants could enhance PFAS removal efficiency. The research team advocates for further exploration into microbial solutions for PFAS remediation.

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